Health Hazards

Health Hazards:

Escherichia coli :

· Incubation: Usually 3-4 days , range 2-12 days
· 1-2nd day: Non Bloody diarrhoea
· 3-10th days: Bloody Diarrhoea (some books write 4-10days)
· Usually self limiting, about 2-3days

Health Implications:
· HUS ( Haemolytic Uraemic Syndrome){Kidney failure)
· TTP ( Thrombolic Thrombocytopenic Purpura) { Platelette count drop}
· Haemorrhagic colitis (Bloody Diarrhoea)

Infectious dose:

· 0.3-15 CFU /g

Listeria monocytogene:
Infant:
· Pneumonia
· Speticaemia (Blood Poisoning)
· Abscesses ( Widely disseminated Granulomas)

Adult:
· Speticaemia
· Meningitis (swelling of Brain Tissue)
· Meningocephalitis
· Endocarditis


Pregnant :
· Influnenza symdromes
· Fever
· Headache
· GI symptoms

Health implications for Pregnant mothers:

· Abortion
· Still birth
· Premature labour

Infectious dose :

· 0.3 CFU-100 CFU /g

Campylobacter jejuni:

· Incubation : 1-11days
· Usually: 3-5days
· Usually Self-limiting to 1 to 3 wks
· Diarrhoea
· Systemic illness
· Guillain-Barre Syndrome

Infectious Dose:
· 1000 CFU /g

Guillain Barre Syndrome:
· Acute Paralysis
· Small portion of people die
· Req. assisted ventilator

Salmonella typhi :
.Cause for typhoid
.Incubation 3-56 days
.Usually 10 -20 days
.Mild fever
.Speticaemia
.Bile infection
.Intestinal Ucle
.Fever
.Diarrhoea
.Infectious dose:
10-100 cells


Salmonella enterditis
Incubation : 6-48 Hrs
Mild fever
Nausea
Diarrhoea
Infectious dose , Less than 200 CFU/g

Clostridium botulinum :

· Incubation: Usually 12-36hr but can be up to 14 days

Health Implications:
· Nausea
· Visual Impairment
· Double vison
· Fixed/ dilated pupil
· Loss of oral function
· Lack of muscle coordination
· Respiratory impairment
· Abdominal pain
· Death

Infectious dose of toxin:

· 0.4ng/kg

Clostridium perfingnes
Incubation: 8-16 hrs
Diarrhoea
Severe abdominal cramp
Spontaneously resolved in 12 to 24 hoursInfectious dose : 10E7 CFU/g